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ctaO [2017-8-11 16:0:3]
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ctaO [2017-8-11 16:0:3]

heme O synthase (minor enzyme)
locus
BSU12080
pI
10.12
mw
36.73 kDa
protein length
329 aa Sequence Blast
gene length
987 bp Sequence Blast
function
heme biosynthesis
product
heme O synthase (minor enzyme)
essential
no
synonyms
yjdK
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.6|Biosynthesis of heme/ siroheme]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,279,514 → 1,280,503

    The protein

    Protein family

  • Protoheme IX farnesyltransferase subfamily (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|83F5D5FCCAFADB7231ACD9BE7941820240954C70|CtaB]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|6CE139563BBD7C1C97AEC3AA3F88146C4EEA79E4|ctaO]
    description
    [Pubmed|21815947]

    regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • additional information

  • the amount of the mRNA is substantially decreased upon depletion of [gene|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [PubMed|21815947]
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    Biological materials

    Mutant

  • MGNA-A273 (yjdK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/273 NBRP B. subtilis, Japan]

    • References

  • 10675592,20817675,21815947